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    Home»Science»Immune cells that stop our body from attacking itself land a Nobel
    Science

    Immune cells that stop our body from attacking itself land a Nobel

    October 8, 20254 Mins Read
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    Line sketches of the three winners of the 2025 Nobel Prize in physiology and medicine from left to right: Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi, The trio won for discovering a type of immune cell.
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    autoimmune: (n. autoimmunity) An adjective to describe inappropriate reactions in which the immune system turns against its host’s body. This can cause disease instead of curing it. Autoimmune diseases can be quite severe and hard to treat. They include rheumatoid arthritis (affecting joints, such as knees), multiple sclerosis (targeting nerves and muscles), Crohn’s disease (affecting the gut), psoriasis and lupus (affecting skin) and the type of diabetes that typically develops in young children. In all of these cases, the immune system generates out-of-control inflammation.

    biology: The study of living things. The scientists who study them are known as biologists.

    cancer: Any of more than 100 different diseases, each characterized by the rapid, uncontrolled growth of abnormal cells. The development and growth of cancers, also known as malignancies, can lead to tumors, pain and death.

    cell: (in biology) The smallest structural and functional unit of an organism. Typically too small to see with the unaided eye, it consists of a watery fluid surrounded by a membrane or wall. Depending on their size, animals are made of anywhere from thousands to trillions of cells.

    develop: (n. development) To emerge or to make come into being, either naturally or through human intervention, such as by manufacturing. (in biology) To grow as an organism from conception through adulthood, often undergoing changes in chemistry, size, mental maturity or sometimes even shape.

    fetus: (Adj. fetal ) The term for a mammal or other large animal during its later-stages of development in the womb. For humans, this term is usually applied after the eighth week of development.

    gene: (adj. genetic) A segment of DNA that codes, or holds instructions, for a cell’s production of a protein. Offspring inherit genes from their parents. Genes influence how an organism looks and behaves.

    immune: (adj.) Having to do with immunity. (v.) Able to ward off a particular infection. Alternatively, this term can be used to mean an organism shows no impacts from exposure to a particular poison or process. More generally, the term may signal that something cannot be hurt by a particular drug, disease or chemical.

    immune system: The collection of cells and their responses that help the body fight off infections and deal with foreign substances that may provoke allergies.

    infection: A disease that can spread from one organism to another. It’s usually caused by some type of microbe.

    mutation: (v. mutate) Some change that occurs to a gene in an organism’s DNA. Some mutations occur naturally. Others can be triggered by outside factors, such as pollution, radiation, medicines or something in the diet. A gene with this change is referred to as a mutant.

    Nobel prize: A prestigious award named after Alfred Nobel. Best known as the inventor of dynamite, Nobel was a wealthy man when he died on December 10, 1896. In his will, Nobel left much of his fortune to create prizes to those who have done their best for humanity in the fields of physics, chemistry, physiology or medicine, literature and peace. Winners receive a medal and large cash award.

    physiology: The branch of biology that deals with the everyday functions of living organisms and how their parts function. Scientists who work in this field are known as physiologists.

    pup: A term given to the young of many animals, from dogs and mice to seals.

    recruit: (noun) New member of a group or human trial. (verb) To enroll a new member into some group or organization. It could be into the military. Or it could be into participating in a research group to test some drug, behavior or environmental condition.

    syndrome: Two or more symptoms that together characterize a particular disease, disorder or social condition.

    system: A network of parts that together work to achieve some function. For instance, the blood, vessels and heart are primary components of the human body’s circulatory system. Similarly, trains, platforms, tracks, roadway signals and overpasses are among the potential components of a nation’s railway system. System can even be applied to the processes or ideas that are part of some method or ordered set of procedures for getting a task done.

    T cells: A family of white blood cells, also known as lymphocytes, that are primary actors in the immune system. They fight disease and can help the body deal with harmful substances.

    tissue: Made of cells, it is any of the distinct types of materials that make up animals, plants or fungi. Cells within a tissue work as a unit to perform a particular function in living organisms. Different organs of the human body, for instance, often are made from many different types of tissues.



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